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MRD Watch

Sunday, November 15, 2026

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Trials

MRD trials

The curated index is a sourced list of studies. Accruing is the live ClinicalTrials.gov recruiting set. DYNAMIC-III is not in the curated index because it is registered in Australia and New Zealand, not with an NCT id.

Recruiting interventional studies whose public record uses ctDNA or MRD to guide treatment, or lists it as a primary endpoint. 110 studies from 454 registry hits. Last synced Nov 14, 2026, 9:51 PM EST.

  • HemePhase 3NCT07222761

    A Study to Compare Linvoseltamab Monotherapy and Linvoseltamab + Carfilzomib Combination Therapy With Standard-of-Care Combination Regimens in Adult Participants With Relapsed/Refractory Multiple Myeloma (RRMM)

    Regeneron Pharmaceuticals · 53 locations · Updated 2026-11-04

  • HemePhase 2NCT05091372

    Minimal Residual Disease Guided Maintenance Therapy With Belantamab Mafodotin and Lenalidomide After Autologous Hematopoietic Cell Transplantation in Patients With Newly Diagnosed Multiple Myeloma

    M.D. Anderson Cancer Center · 1 locations · Updated 2026-11-02

  • HemePhase 2NCT07021989

    ctDNA-Guided Therapy for Relapsed/Refractory Hodgkin Lymphoma

    Michael Spinner, MD · 6 locations · Updated 2026-10-20

  • HemePhase 2NCT07409454

    MRD-Guided BCMA/CD3 Bispecific Antibody Treatment After Stem Cell Transplant for Newly Diagnosed Multiple Myeloma

    Institute of Hematology & Blood Diseases Hospital, China · 1 locations · Updated 2026-08-07

  • HemePhase 2NCT06483100

    Measurable Residual Disease-Guided Post-Transplant Elranatamab Maintenance

    Washington University School of Medicine · 1 locations · Updated 2026-08-06

  • HemePhase 2NCT07671378

    A Study of MRD-Guided Zanubrutinib Plus Sonrotoclax in Treatment-Naïve, High-Risk CLL/SLL Patients

    The First Affiliated Hospital with Nanjing Medical University · 1 locations · Updated 2026-06-26

  • HemePhase 2NCT06974786

    Frontline T-cell Engager vs Autologous Stem Cell Transplant (ASCT) and Measurable Residual Disease (MRD)-Guided Sequential Intensification thERapy in Multiple Myeloma

    SCRI Development Innovations, LLC · 11 locations · Updated 2026-06-04

  • HemePhase 3NCT07463651

    MRD-guided Maintenance Post-HCT: Gilteritini vs Sorafenib

    The First Affiliated Hospital of Soochow University · 2 locations · Updated 2026-03-20

  • HemePhase 2NCT07259707

    Gilteritinib Plus VA Followed By Consolidation Chemotherapy in Newly Diagnosed FLT3-ITD+ AML

    First Affiliated Hospital of Zhejiang University · 1 locations · Updated 2026-02-04

  • HemeNot applicableNCT06693830

    ctDNA-guided Therapy Optimization in Newly Diagnosed DLBCL

    Hua-Jay J Cherng, MD · 1 locations · Updated 2026-01-23

  • HemePhase 2NCT06828991

    A Study to Evaluate the Impact of Mosunetuzumab Consolidation for Older Patients With Diffuse Large B-cell Lymphoma (DLBCL) Who Have Detectable Amounts of ctDNA (Circulating Tumor DNA) at the End of Treatment With Pola-R-mini-CHP

    Danielle Wallace · 1 locations · Updated 2025-10-20

  • HemePhase 1 / Phase 2NCT06902012

    Safety and Efficacy of Early Second Infusion of Axi-cel Based on ctDNA for R/R Large B - Cell Lymphoma

    Zhujiang Hospital · 1 locations · Updated 2025-03-30

  • HemePhase 2 / Phase 3NCT04513639

    The Relapse from MRD Negativity As Indication for Treatment (REMNANT) Study

    Oslo University Hospital · 13 locations · Updated 2025-03-20

  • HemePhase 2NCT06574126

    Ciltacabtagene Autoleucel in High-Risk Smoldering Multiple Myeloma

    PETHEMA Foundation · 1 locations · Updated 2024-10-26

  • HemePhase 2NCT06158269

    DVRd in the Treatment of Patients With Newly Diagnosed Double-hit Multiple Myeloma

    Institute of Hematology & Blood Diseases Hospital, China · 1 locations · Updated 2023-12-06

  • HemePhase 2NCT04758975

    Venetoclax, Rituximab and Ibrutinib in TN Patients With CLL Undetectable Minimal Residual Disease (uMRD) in Treatment-naïve Patients With Chronic Lymphocytic Leukemia (CLL)

    Paolo Ghia · 1 locations · Updated 2023-10-04

  • HemePhase 2NCT07106736

    MRD-Adaptive Guided Immunotherapy With CAR-T for Transplant-Ineligible Patients With Multiple Myeloma

    Institute of Hematology & Blood Diseases Hospital, China · 1 locations · Updated 2026-10-27

  • HemePhase 2NCT06745076

    Personalized Reduction of Chemotherapy Intensity Through ctDNA Evaluation for the Treatment of Patients With Advanced Hodgkin Lymphoma

    University of Washington · 6 locations · Updated 2026-09-09

  • HemePhase 2NCT06207799

    Pre-transplant Purging and Post-transplant MRD-guided Maintenance Therapy With Elranatamab in Patients With High-risk Multiple Myeloma

    M.D. Anderson Cancer Center · 1 locations · Updated 2026-08-10

  • HemeNot applicableNCT06898905

    Hyperfractionated Dual Equivalent Fractionated Radiation Therapy

    Yale University · 1 locations · Updated 2026-06-22

  • HemePhase 2NCT07507318

    Chidamide Maintenance for MRD-Positive Double-Expressor DLBCL in First Complete Remission

    Rong Tao · 1 locations · Updated 2026-06-18

  • HemePhase 2NCT06954805

    Defining ctDNA Metrics in Posttransplant Lymphoproliferative Disorder (PTLD)

    Jennifer Amengual · 2 locations · Updated 2026-05-27

  • HemePhase 2NCT06050694

    Feasibility Trial of Glofitamab in a Response Adapted Approach Incorporating Interim FDG PET and ctDNA to Optimize Primary Therapy of DLBCL (GRAIL)

    University Health Network, Toronto · 3 locations · Updated 2026-04-24

Status can change after this sync. The curated list is the other view on this page. Evidence holds the published results.