Trials
MRD trials
The curated index is a sourced list of studies. Accruing is the live ClinicalTrials.gov recruiting set. DYNAMIC-III is not in the curated index because it is registered in Australia and New Zealand, not with an NCT id.
Recruiting interventional studies whose public record uses ctDNA or MRD to guide treatment, or lists it as a primary endpoint. 110 studies from 454 registry hits. Last synced Nov 14, 2026, 9:51 PM EST.
Circulating Tumor DNA Methylation-Guided Adjuvant Therapy Decision-Making in Patients With Resectable Colorectal Cancer Liver Metastases After Resection
Fudan University · 1 locations · Updated 2026-11-04
ctDNA-Guided Sunitinib And Regorafenib Therapy for GIST
University of Miami · 1 locations · Updated 2026-10-23
Fluorescence Image Guided Surgery Followed by Intraoperative Photodynamic Therapy for Improving Local Tumor Control in Patients With Locally Advanced or Recurrent Colorectal Cancer
Roswell Park Cancer Institute · 1 locations · Updated 2026-10-15
ctDNA-Guided Immunotherapy for dMMR/MSI-H Colon Cancer
Fudan University · 1 locations · Updated 2026-09-25
Study of ctDNA Guided Change in Tx for Refractory Minimal Residual Disease in Colon Adenocarcinomas
University of California, Irvine · 1 locations · Updated 2026-05-11
RESPONSE: Colorectal Cancer Survivors' Follow-up Care - Now Digital and Need-based
University of Aarhus · 9 locations · Updated 2026-05-04
Randomized Trial of Plasma ctDNA Methylation-Guided Adjuvant Therapy in T4N0 and Low-Risk Stage III Colorectal Cancer
Fudan University · 1 locations · Updated 2026-05-01
A Randomized Controlled Trial of Plasma ctDNA Methylation-Guided Adjuvant Chemotherapy Decision-Making in High-Risk Stage III (T4N+ or T1-3N2) Colorectal Cancer
Fudan University · 1 locations · Updated 2026-05-01
Randomized Controlled Study of Plasma ctDNA Methylation-Guided Adjuvant Chemotherapy in Stage I/Low-Risk Stage II Colorectal Cancer
Fudan University · 1 locations · Updated 2026-05-01
FOLICOLOR TRIAL: Following Therapy Response Through Liquid Biopsy in Metatstatic Colorectal Cancer Patients
University Hospital, Antwerp · 9 locations · Updated 2026-04-30
Dynamic Circulating Tumor DNA Monitoring to Guide Systemic Therapy in Gastric Cancer
Fudan University · 1 locations · Updated 2026-04-08
Implementing ctDNA and Circular DNA in Patients With Localized Pancreatic Cancer
Copenhagen University Hospital at Herlev · 5 locations · Updated 2026-03-27
Circulating Tumor DNA Methylation Guided Postoperative Follow-up Strategy for Non-metastatic Colorectal Cancer
Fudan University · 1 locations · Updated 2025-09-18
Adjuvant Pancreatic Therapy Guided by MRD
Ruijin Hospital · 1 locations · Updated 2025-07-15
ctDNA-Guided Cetuximab or Bevacizumab Plus Trifluridine/Tipiracil in RAS/BRAF Wild-Type mCRC
Sun Yat-sen University · 1 locations · Updated 2025-06-24
The ctDNA-RECIST Trial Part One
Karen-Lise Garm Spindler · 2 locations · Updated 2025-05-01
Circulating Tumor DNA-guided Neoadjuvant Treatment Strategy for Locally Advanced Rectal Cancer
Peking Union Medical College Hospital · 1 locations · Updated 2024-12-24
Developing ctDNA Guided Adjuvant Therapy for Gastrooesophageal Cancer
University of Southampton · 14 locations · Updated 2024-11-12
ctDNA-guided Selection of Adjuvant Chemotherapy Regimens for Elderly Colon Cancer Patients After Surgery: A Single-center, Randomized, Controlled Study
Zhejiang Cancer Hospital · 1 locations · Updated 2024-09-24
OPTIMIzation of Treatment SElection and Follow up in Oligometastatic Colorectal Cancer
Karen-Lise Garm Spindler · 2 locations · Updated 2024-08-14
Circulating Tumor DNA Methylation Guided Postoperative Adjuvant Chemotherapy for High-risk Stage II/III Colorectal Cancer
Fudan University · 1 locations · Updated 2024-05-20
Circulating Tumor DNA Methylation Guiding Postoperative Adjuvant Chemotherapy in Stage III Colorectal Cancer
Sir Run Run Shaw Hospital · 1 locations · Updated 2024-05-17
MRD-guided Deferred Adjuvant Therapy in Resectable Early-stage Colon Cancer
Sun Yat-sen University · 1 locations · Updated 2024-01-12
ctDNA-guided Adjuvant Chemotherapy in Liver Metastasis of Colorectal Cancer
Sixth Affiliated Hospital, Sun Yat-sen University · 1 locations · Updated 2023-04-18
The Value of Molecular Residual Disease Monitoring Based on ctDNA in Borderline Resectable or Locally Advanced Pancreatic Cancer
Peking Union Medical College Hospital · 1 locations · Updated 2023-04-12
The Value of Molecular Residual Disease Monitoring Based on ctDNA in Resected Pancreatic Cancer
Peking Union Medical College Hospital · 1 locations · Updated 2023-04-12
Postoperation Maintenance Therapy for Resectable Liver Metastases of Colorectal Cancer Guided by ctDNA
Sixth Affiliated Hospital, Sun Yat-sen University · 1 locations · Updated 2023-04-04
Systemic Neoadjuvant and Adjuvant Control by Precision Medicine in Rectal Cancer
Helsinki University Central Hospital · 2 locations · Updated 2023-03-06
Circulating Tumor DNA Guided Adjuvant Chemotherapy for Colon Cancer
Peking University Cancer Hospital & Institute · 1 locations · Updated 2022-09-07
Anti-CEA CAR-T Cells to Treat Colorectal Liver Metastases
Changhai Hospital · 1 locations · Updated 2022-03-11
EUS Guided HVA and PVA for Circulating Tumor DNA in Patients
Chinese University of Hong Kong · 1 locations · Updated 2021-03-04
Colon Adjuvant Chemotherapy Based on Evaluation of Residual Disease
NRG Oncology · 1085 locations · Updated 2026-11-04
ctDNA Monitoring in Patients With HCC and mCRC
Medical University of Warsaw · 1 locations · Updated 2025-06-03
Pilot Comparing ctDNA IDV vs. SPV Sample in Pts Undergoing Biopsies for Hepatobiliary and Pancreatic Cancers
University of California, Irvine · 1 locations · Updated 2026-08-31
Liquid Biopsies in Esophageal Cancer
Universitaire Ziekenhuizen KU Leuven · 4 locations · Updated 2026-06-01
A Multicenter Prospective Study Evaluating Concurrent Chemoradiotherapy Following Induction Immunochemotherapy for Esophageal Cancer Based on Dynamic ctDNA Monitoring
The Central Hospital of Lishui City · 2 locations · Updated 2026-03-23
Status can change after this sync. The curated list is the other view on this page. Evidence holds the published results.