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MRD Watch

Sunday, November 15, 2026

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Cancer type

Liver / HCC

Liver cancer and hepatocellular carcinoma.

Must-know

  1. 1

    Serial ctDNA and recurrence in hepatocellular carcinoma

    Zhu et al. Molecular Oncology. 2022.

    In this prospective study, preoperative ctDNA and the median variant allele fraction at baseline were independent predictors of recurrence-free survival.

    PMID 34543520DOI

A randomized ctDNA-guided hepatocellular carcinoma trial was not identified.

Listed when a study is a randomized or prospective interventional ctDNA or MRD trial, is cited in NCCN or ESMO guidance, or is a prospective validation cohort in a high-impact journal. Shorter lists mean fewer studies met that rule. No test is ranked.

Trials

  • Recruiting · Not applicable

    NCT07001085 ctDNA monitoring in hepatocellular carcinoma and metastatic colorectal cancer

    Interventional study of serial ctDNA in hepatocellular carcinoma and in colorectal cancer metastatic to the liver. The registry lists the phase as not applicable and the primary outcome as assessment of the clinical value of the ctDNA level. ClinicalTrials.gov lists the study as recruiting.

No Colorectal and GI updates are on file for this filter.